Tumores Malignos da Vesícula Biliar. Revisão da Literatura e Análise de 10 Anos no Instituto Nacional de Câncer do Rio de Janeiro

Authors

  • Márcio Cezar Botelho Nascimento Médico Assistente. Seção de Cirurgia Abdominopélvica. Instituto Nacional de Câncer (INCA). Rio de Janeiro (RJ), Brasil
  • Alemar Roge Salomão Chefe. Seção de Cirurgia Abdominopélvica. Instituto Nacional de Câncer (INCA). Rio de Janeiro (RJ), Brasil
  • Marco Antonio Moraes do Carmo Médico Assistente. Seção de Cirurgia Abdominopélvica. Instituto Nacional de Câncer (INCA). Rio de Janeiro (RJ), Brasil
  • Carlos Eduardo Pinto Médicos Residentes em Cirurgia. Seção de Cirurgia Abdominopélvica. Instituto Nacional de Câncer (INCA). Rio de Janeiro (RJ), Brasil

DOI:

https://doi.org/10.32635/2176-9745.RBC.1982v29n2.3532

Keywords:

Gallbladder Neoplasms, Cancer Care Facilities, Surgical Oncology

Abstract

The records of 19 cases of primary malignant neoplasms of the gallbladder seen at the Instituto Nacional de Cancer (1962-1972) were reviewed. All of them but one were adenocarcinomas. The female/male ratio was 3,5:1 and the lesion was predominant in elder patients. The tumor was associated with colelithiasis in 10 cases. The best results were obtained in patients with cancer discovered at surgery for benign biliary disease. Twelve cases were lost to follow-up. Early diagnosis is very difficult and we believe that any chance of improving the results seen at our series and those of the literature wiH lie in the advance of new chemotherapy protocols and in progress of propedeutic methods for early diagnosis, where surgery plays an important role.

Downloads

Download data is not yet available.

References

ACKERMAN, L.V. — Carcinoma of the gallbladder in Del Regato, J.A. e Spjut.H. J. — Cancer; diagnosis, treatment and prognosis — St. Louis, C.V. Mosby, 1977, pág. 598.

ADSON. M.A. — Carcinoma of the gallbladder. Surg. Clin. North Am. 53: 1203, 1973. DOI: https://doi.org/10.1016/S0039-6109(16)40147-7

AL-SARRAF, M.; BAKER, L et al. — The value of serial carcinoembryonic antigen (CEA) in predicting response rate and survival of patients with gastrointestinal cancer treated with chemotherapy. Cancer 44: 1222, 1979. DOI: https://doi.org/10.1002/1097-0142(197910)44:4<1222::AID-CNCR2820440409>3.0.CO;2-X

AOKI. Y.; OKAMURA, T.et al.- Papilloma of the gallbladder. Am. J. Surg. 131: 614, 1976. DOI: https://doi.org/10.1016/0002-9610(76)90027-1

APPLEMAN, R.M.; MORLOCK, C. G. et al. — Longterm survival in carcinoma of the gallbladder. Surg. Gyn. Obst. 117: 459, 1963.

BURROWS, H. — Gallstones and cancer: a problem of etiology with special reference to the role of irritation. Br. J. Surg. 27: 1116, 1939. DOI: https://doi.org/10.1002/bjs.18002710517

GLENN, F.; HAYS.,D. M. – The scope of radical surgery in treatment of malignant tumors of the extra hepatic biliary tracts. Surg. Gyn. Obst. 99: 529, 1954.

GLENN, F.— Silent gallstones. Ann. Surg. 1936 (2): 251, 1981. DOI: https://doi.org/10.1097/00000658-198102000-00022

HARDY, M.A.; VOLK, H. - Primary carcinoma of the gallbladder; a ten year review. Am. J. Surg. 120: 800, 1970. DOI: https://doi.org/10.1016/S0002-9610(70)80053-8

KIELL, R.H.; DE WEESE, M.S. - Primary carcinoma of the gallbladder. Am. J. Surg. 125: 726, 1973. DOI: https://doi.org/10.1016/0002-9610(73)90173-6

MOERTEL, C.G.-The gallbladder. In Holland J.F. — Cancer Medicine, Philadelphia, Lea & Febiger, 1973.

MOOSA, A.T.; ANAGUOST et al. The continuing challenge of gallbladder cancer; survey of 30 year's experience at the University of Chicago. Am. J. Surg. 130: 57, 1975. DOI: https://doi.org/10.1016/0002-9610(75)90458-4

NEVIN, J.E.; MORAN, T. J. et al. — Carcinoma of the gallbladder; staging, treatment and prognosis. Cancer 37: 141, 1976. DOI: https://doi.org/10.1002/1097-0142(197601)37:1<141::AID-CNCR2820370121>3.0.CO;2-Y

PACK, G.T. — Right hepatlc lobectomy for cancer of the gallbladder. In Pack G.T. & Arie I.M. - Treatment of Câncer and Allied Diseases, N. York, Harper & Row Publishers, 1964.

PEMBERTON, L. B.; DIFFENBAUGH, W.F. et al. — Surgical significance of the carcinoma of the gallbladder. Am. J. Surg. 122: 381, 1971. DOI: https://doi.org/10.1016/0002-9610(71)90263-7

PEISON, B.; RABIN, L. - Malignant melanoma of the gallbladder; report of 3 cases and review of the literature. Cancer 37: 2448, 1976. DOI: https://doi.org/10.1002/1097-0142(197605)37:5<2448::AID-CNCR2820370538>3.0.CO;2-Q

PETROV, N.N.; KROTNIKA, N.A. — Experimental carcinoma of the Gallbladder; supplementary data. Am. J. Surg. 125: 241, 1947. DOI: https://doi.org/10.1097/00000658-194702000-00010

SHERLOK, S. — Doenças do fígado e das vias biliares, 5ª ediçáo. Rio de Janeiro, Guanabara Koogan, 1978.

SOSIN, H. — Los cálculos silenciosos de Ia vesicula biliar deben ser tratados por colecistectomia? In Delaney J.P. & Najarian J.S. — Cirurgia del higado, pancreas e vias biliares, Barcelona, Editorial Científico-Medica, 1978, 73-79.

STRAUCH, J. — citado por Appleman (referência 5).

SWINTON, N.; BECKER, W.F. - Tumors of the gallbladder. Surg. Clin. North. Am. 28: 669, 1939. DOI: https://doi.org/10.1016/S0039-6109(16)32440-9

TABAH, E.J.; McNEER, G. - Papilloma of the gallbladder with in situ carcinoma. Surgery 34: 57, 1953.

TANGA, M.R.; EWING, J.B. - Primary malignant tumors of the gallbladder; report of 43 cases. Surgery 67: 418, 1970.

TREADWELL, T.A.; HARDIN, W. J. — Primary carcinoma of the gall bladder; The role of adjunctive therapy in its treatment. Am. J. Surg. 132: 102, 1976. DOI: https://doi.org/10.1016/0002-9610(76)90439-6

WARREN, K.W.; HARDY, K.J. et al.- Primary neoplasia of the gallbladder. Surg. Gyn. Obst. 126: 1036, 1968.

Published

2023-08-10

How to Cite

1.
Nascimento MCB, Salomão AR, Carmo MAM do, Pinto CE. Tumores Malignos da Vesícula Biliar. Revisão da Literatura e Análise de 10 Anos no Instituto Nacional de Câncer do Rio de Janeiro. Rev. Bras. Cancerol. [Internet]. 2023 Aug. 10 [cited 2024 May 17];29(2):12-7. Available from: https://rbc.inca.gov.br/index.php/revista/article/view/3532

Issue

Section

LITERATURE REVIEW

Most read articles by the same author(s)