Review article: chromosomal diagnosis in rhabdomyosarcoma

Autores/as

  • Plínio Cerqueira dos Santos Cardoso Departamento de Genética, Faculdade de Medicina de Ribeirão Preto - Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP.
  • Marcelo de Oliveira Bahia Departamento de Genética, Faculdade de Medicina de Ribeirão Preto - Universidade de São Paulo (FMRP-USP), Ribeirão Preto, SP. Ciências Biológicas, Universidade Federal do Pará, Belém, PA.
  • Marcelo Razera Baruffi Departamento de Pediatria (FMRP-USP), Ribeirão Preto, SP.
  • Juliana Simão Nina de Azevedo Ciências Biológicas, Universidade Federal do Pará, Belém, PA.
  • André Salim Khayat Ciências Biológicas, Universidade Federal do Pará, Belém, PA.
  • Marilia de Arruda Cardoso Smith Disciplina de Genética, Departamento de Morfologia, Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, SP.
  • Paulo Pimentel de Assumpção Serviço de Cirurgia, Hospital Universitário João de Barros Barreto (UFPA), Belém, PA.
  • Rommel Rodríguez Burbano Ciências Biológicas, Universidade Federal do Pará, Belém, PA. Disciplina de Genética, Departamento de Morfologia, Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, SP.
  • Luiz Gonzaga Tone Departamento de Pediatria (FMRP-USP), Ribeirão Preto, SP.

DOI:

https://doi.org/10.32635/2176-9745.RBC.2005v51n1.1998

Palabras clave:

Chromosomes, Cytogenetics, Rhabdomyosarcomas

Resumen

Rhabdomyosarcomas (RMS) are considered clinically aggressive tumors, originated from immature mesenchymal cells and characterized by the presence of cells with an ill-defined differentiation. The use of conventional cytogenetic techniques has contributed considerably to distinguish the alveolar RMSs from the other types of solid tumors in children and adolescents. Besides that, it provides important prognostic informations about alveolar RMSs. Thus, the present work was aimed at reviewing the cytogenetic alterations observed in the different histological subtypes of RMS, focusing not only on the studies performed with conventional cytogenetics, but also on new approaches used in the study of neoplasms, such as FISH, CGH, SKY and M-FISH. These methodologies have contributed significantly to a better understanding of the karyotype heterogeneity observed in RMS.

Descargas

Los datos de descargas todavía no están disponibles.

Descargas

Publicado

2005-03-31

Cómo citar

1.
Cardoso PC dos S, Bahia M de O, Baruffi MR, Azevedo JSN de, Khayat AS, Smith M de AC, Assumpção PP de, Burbano RR, Tone LG. Review article: chromosomal diagnosis in rhabdomyosarcoma. Rev. Bras. Cancerol. [Internet]. 31 de marzo de 2005 [citado 22 de julio de 2024];51(1):59-65. Disponible en: https://rbc.inca.gov.br/index.php/revista/article/view/1998

Número

Vol. 51 Núm. 1 (2005): ene./feb./mar.

Sección

REVISIÓN DE LA LITERATURA

Licencia

Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.

Artículos más leídos del mismo autor/a