Low-Level Laser Therapy in Vulvovaginal Symptoms Induced by Graft-Versus-Host Disease: Case Report
DOI:
https://doi.org/10.32635/2176-9745.RBC.2024v70n2.4648Keywords:
Genital Diseases, Female/radiotherapy, Hematopoietic Stem Cell Transplantation/adverse effects, Host vs Graft Reaction/immunology, Low-Level Laser Therapy/methodsAbstract
Introduction: In the literature, vulvovaginal graft versus host disease (GVHD) has an incidence that varies between 24.9 and 69% and there are not many studies addressing this topic. Photobiomodulation (FBM) for vulvovaginal GVHD has not been described in the literature to date, but there is evidence of its effectiveness in oral GVHD and in the prevention of cancer-related oral mucositis. The objective of this study was to describe the evaluation and physical therapy treatment with FBM of a patient diagnosed with vulvovaginal GVHD. Case report: Woman with vulvovaginal GVHD complaining of moderate pain when urinating, difficulty performing intimate hygiene, burning sensation in the vulva and severe discomfort when wearing underwear. FBM favored the improvement of pain and tissue repair of vulvar injuries, relieving symptoms and
facilitating the performance of vaginal dilation exercises. Conclusion: FBM was appropriate and effective in reducing pain, burning sensation and discomfort, providing an anti-inflammatory and tissue regenerating effect. This resulted in a perceived improvement in other complaints related to the use of underwear and intimate hygiene. However, for the laser to become a strongly recommended resource in this scenario, more robust studies are needed, with longer intervention and follow-up times, as randomized and controlled clinical trials.
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